Chem 3: Drawing Molecules
BioMol 1: Intro
Biomol 2: Protein
Review
Supplementary Material

Chem 3 Companion Questions

BioMol 2 Companion Questions (this is on the 3rd tab)

Topic specific notes. In biology:

steriochemistry is optional. You will be neither penalized nor awarded extra points in this course.
show all bonds, don't leave OH as is.

We will be using and discussing the common molecules found in organisms throughout the semester, so it's important to gain some fundamental understanding of these major molecule classes. This first video will introduce you to some common elements to these molecule.

Part I - Intro: Polymers and The most common reaction

Learning objectives

Know the major classes
Know what a polymer & monomer mean
Understand the 2 major chemical reactions: condensation & hydrolysis

Openstax Ch 2.4 - while the chapter reading corresponds to the lecture topic in the video, the timeline of the video skips through the content of the textbook (they are not aligned) and may not cover everything in the textbook. Make an effort to read the entire chapter. Some content you are responsible for, may (unlikely) be covered only in the textbook.

While progressing through this course, keep in mind that science is all about finding patterns (Theories) and applying them (making predictions). You should apply this to learning too. The first videos on proteins are very dense and in-depth. You are also expected to memorize more information. However, many of these concepts apply to other molecules in the future. Memorizing it for proteins serves as practice, it gives you some idea of how it works, and it gives you a template for understanding other similar situations. As we progress through the course (when we look at other BioMolecules) we will cover less, instead you will think (I will say):

"This is probably similar to proteins, I could memorize it too, but I'll probably never use it. I'll memorize if I start using it in my daily work someday. But good thing I did proteins, because I'll be able to figure it out when the time comes."

BioMol 2 Companion Questions

Learning Objectives

Know the "function" of proteins
Know that proteins are polypeptides of amino acids & corresponding terminology
Memorize the structure of an amino acid
Given R, be able to draw an amino acid using "unabbreviated" chemical symbols
Know the special way amino acids are classifies
Be able to classify amino acids
Be able to show how different molecules might interact with amino acids based on that classification
Know what a zwitterion is, get a sense of pKa, but don't worry about it.
Be able to show the STEPWISE joining of amino acids
Understand directionality and what N-ter & C-ter are
Know and explain the 4 levels of protein structure
Know the basis for protein structure
Know what a disulfide bond is
Know why proteins are able to change their shape
BIOLOGY THEME: Structure = function
- be prepared to elaborate and give course specific examples
Be able to interpret the different kinds of protein models (ribbon, ball & stick, space-filling)

Openstax Ch 2.5- Not in order and will cover the next few lectures.

Some additional relevant Terminology

backbone
alpha carbon
R-group / side-chain
mono- di- tri-
alpha-helix
beta-sheet
attachment point
denatured
native

The following video should serve as summary / review. You should watch these to make sure you understood the key points. These are the videos you should use if you want a review for the test. They can also be found in the "Study Materials" section of the file bank.

Drawing Molecules / Molecular Interactions

Joining (condensation / dehydration synthesis) and Breaking (hydrolysis) reactions
and proteins